In a key vote on Wednesday, Senate Republicans moved to block the long-anticipated bipartisan border deal, which ties border-security provisions to aid for both Israel and Ukraine.

The bill was blocked in a 49 to 50 procedural vote, with only four Republicans joining Democrats in backing the legislation.

This setback comes after months of negotiations between Senate Republicans and Democrats on a measure that President Joe Biden strongly requested for months.

Senators James Lankford of Oklahoma, Lisa Murkowski of Alaska, Susan Collins of Maine, and Mitt Romney of Utah were the only Republicans to vote in favor of the bill.

Meanwhile, Democratic senators Alex Padilla of California, Bob Menendez of New Jersey, Elizabeth Warren of Masachusetts, and Ed Markey of Massachusetts voted against the measure, as did independent senator Bernie Sanders of Vermont.