The United States and Iran are at odds ahead of anticipated nuclear negotiations, with Tehran declaring uranium enrichment a “non-negotiable” right even as Supreme Leader Ayatollah Ali Khamenei has authorized renewed talks. Here’s what you need to know about this developing diplomatic situation:

The negotiating positions

Fundamental differences already apparent:

The Supreme Leader’s role

Khamenei’s involvement signals significant shift:

The Trump approach

New administration brings different strategy:

The enrichment reality

Technical situation complicates talks:

The regional context

Broader Middle East dynamics affect calculations:

The domestic pressures

Internal politics shape both countries’ approaches:

The diplomatic timeline

Process taking shape amid tensions:

What happens next

Several key developments are anticipated:

Read more:

• U.S., Iran at odds ahead of nuclear talks; Tehran says uranium enrichment ’non-negotiable’

• Ayatollah Ali Khamenei, Iranian supreme leader, says nuclear talks with U.S. can proceed

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The Washington Times AI Ethics Newsroom Committee can be reached at aispotlight@washingtontimes.com.