Iranian Supreme Leader Ali Khamenei appeared to reject the framework of the United States’s proposal for a new deal relating to his nation’s nuclear enrichment programs.

In a Wednesday speech, the ayatollah dismissed the plan given to Iranian officials by White House special envoy Steve Witkoff on Saturday as “nonsense.” The plan reportedly would slowly wind down the nation’s nuclear enrichment for a temporary period before eventually ceasing the process.

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“There is one point that is a key element in the nuclear industry, and that is uranium enrichment,” Khamenei said in his speech. “A nuclear industry without enrichment capabilities is useless because we would then be dependent on others to obtain fuel for our power plants.”

The speech was the ayatollah’s first remarks on the nuclear deal negotiations since Witkoff delivered the term sheet over the weekend, and it suggests the Iranian negotiating team is going to send the White House back to the drawing board.

Khamenei asserted that the “current nuclear talks that are being mediated by Oman” undercut his nation’s self-sufficiency and autonomy.

“Thousands of nuclear scientists and researchers have been trained in Iran,” he said in his speech. “Should we disappoint them, make them unemployed, and take away their hope in our country’s future? The rude, insolent U.S. leaders want this.”

“You Americans possess atomic bombs and have the massive destruction of the world at your disposal,” he added. “What business is it of yours whether the Iranian nation should or shouldn’t have uranium enrichment or whether it should or shouldn’t have a nuclear industry?”

Khamenei maintains total and unobstructed control over every facet of the Iranian government as an autocratic head of state. It would be impossible for the Iranian government to agree to any deal proposed by the U.S. without the supreme leader’s approval.

While the supreme leader stopped short of declaring an end to the nuclear talks with the U.S., his rejection of the White House’s most foundational terms would require President Donald Trump’s administration to start virtually from scratch.

Trump has said repeatedly that he prefers to resolve the Iranian nuclear issue through peaceful diplomacy, but he has left the door open to more belligerent measures if he feels the rogue Islamic government is incapable of being persuaded.

In April, reports surfaced that the Israeli government intended to conduct a strike on Iranian nuclear facilities but were “waved off” by the White House.

“I wouldn’t say ‘waved off,’” Trump said when asked about his role in pausing that purported operation. “I am not in a rush to do it because I think Iran has a chance to have a great country and to live happily without death, and I’d like to see that. That’s my first option. If there’s a second option, I think it would be very bad for Iran — and I think Iran is wanting to talk.”

Last week, the president once again explicitly mentioned the possibility of a targeted strike on Iranian nuclear infrastructure.

“They don’t want to be blown up,” Trump said. “They would rather make a deal, and I think that could happen in the not-too-distant future. That would be a great thing if we could have a deal without bombs being dropped all over the Middle East. That would be a very good thing.”

TRUMP SAYS US STOCKPILING WEAPONS AT HISTORIC RATE AFTER WARNING IRAN WILL NEVER ENRICH URANIUM

Iran is repairing its air defense systems that were damaged in a counterstrike from Israel after the Iranian government fired missiles at the Jewish state during the height of its conflict with Hamas.

Its current defensive capabilities against targeted airstrikes are unclear.