A new study posted to Preprints.org delivers yet another damning blow to the already crumbling narrative surrounding Covid mRNA injections — and serves as a critical piece of evidence in the growing case against their continued use. Titled “Synthetic mRNA Vaccines and Transcriptomic Dysregulation: Evidence from New-Onset Adverse Events and Cancers Post-Vaccination,” the analysis reveals sweeping, long-lasting genetic disruptions in patients who developed severe side effects or cancer after receiving mRNA Covid shots by Pfizer or Moderna. This, according to the study, points toward mitochondrial dysfunction, immune reprogramming, and the activation of cancer pathways.
The research team spans multiple institutions: Neo7Bioscience, the University of North Texas, the McCullough Foundation, and Medicinal Genomics. It includes respected scientists like Dr. Peter McCullough, Dr. John Catanzaro, and geneticist Kevin McKernan. Together, using high-resolution RNA sequencing, they examined blood samples from individuals harmed following vaccination.
As described by one of the co-authors of the study, Nicolas Hulscher of the McCullough Foundation, the team collected blood from:
Using cutting-edge RNA sequencing tools, the scientists looked at how genes were turned on or off across these groups. The results showed an astounding level of disruption in the vaccine-injured patients. Per Hulscher:
We found that COVID-19 “vaccines” severely disrupted the expression of thousands of genes — inducing mitochondrial failure, immune system reprogramming, and oncogenic activation that persisted for months to years after injection.
What exactly went wrong at the cellular level — and what does it mean for long-term health?
The human body relies on a delicate balance of gene activity to maintain health. Genes control everything from energy production and immune response to cell growth and repair. Upsetting that balance sets the stage for chronic disease and even cancer.
This study found that Covid-19 mRNA vaccines do exactly that, triggering persistent cellular stress and malfunction, including the following issues:
In patients who developed new symptoms after vaccination, the study revealed dysfunction in genes tied to mitochondria — tiny power plants inside our cells. This can reduce energy production and generate harmful byproducts known as reactive oxygen species (ROS), a hallmark of fatigue, neurodegeneration, and metabolic damage.
The mRNA vaccines use a chemically modified synthetic code to make the spike protein. But this artificial code may overload the body’s protein-making machinery. The study showed overactivation of ribosomes and surveillance systems trying to manage translation errors and faulty proteins. This kind of cellular stress can set off internal alarms and cause inflammation.
To compensate, the body ramps up its proteasome system, which clears away defective or misfolded proteins. However, persistent overactivation of this system is often seen in neurodegenerative diseases and can itself lead to inflammation and tissue damage.
The vaccinated individuals showed signs of chronic immune activation. In those with new-onset symptoms, genes controlling inflammatory signaling were abnormally elevated. In cancer patients, the pattern was even more intense, showing sustained activation of immune pathways involving toll-like receptors and type I interferons. These signals, while critical for fighting viruses, can damage tissues when stuck in overdrive and may even help tumors escape immune detection.
Perhaps the most concerning finding was the simultaneous activation of some tumor-promoting genes that normally help prevent cancer. These patterns point to a cellular environment primed for uncontrolled growth.
In the participating cancer patients, the study detected additional hallmarks of genomic instability and epigenetic reprogramming. Those signify deep changes in how the DNA itself is organized and expressed. Scientists often observe these changes during the early stages of tumor development. One possible cause, the study suggests, is the detection of foreign or fragmented genetic material from the vaccine, which could lead to inflammatory and DNA-damage responses.
Both injured groups also showed sharply reduced ACE2 expression. ACE2 is a protein found on the surface of many cell types, where it helps maintain cardiovascular and immune system balance by regulating inflammation and blood pressure. When ACE2 expression drops, it triggers a chain reaction that fuels chronic inflammation and, in cancer models, drives tumor growth and progression.
According to Hulscher, this is the first study to clearly show how mRNA vaccines may cause deep and lasting disruptions to gene expression in certain individuals.
If confirmed by future studies, this research suggests that mRNA injections:
The authors argue that these findings justify “the immediate withdrawal of these dangerous gene therapies.” They warn that the remaining unboosted population – estimated at around 20 percent — should be spared further harm.
Despite growing scientific warnings, unconstitutional federal health authorities continue to double down.
The new leadership at the Department of Health and Human Services (HHS) and the Food and Drug Administration (FDA) came into power on the promise to “Make America Healthy Again” (MAHA) by addressing chronic disease and reforming the nation’s corrupt regulatory systems. But many now see that promise as broken.
Just weeks ago, the FDA granted full approval to Moderna’s mRNA shot for use in “at-risk” children. And in May, the FDA approved Moderna’s booster for use in all adults 65 and older, as well as individuals aged 12-64 years with at least one underlying “risk factor.”
At the same time, HHS and its subordinate agencies are advancing the next generation of mRNA-based products, including those for Covid (project “NextGen”), and broadening the focus to other gene therapies.
Meanwhile, calls are mounting to repeal PREP Act provisions that shield Covid vaccine makers from liability. A new bill by Reps. Thomas Massie (R-Ky.) and Paul Gosar (R-Ariz.) argues those protections must end. They say the government can’t keep covering for manufacturers while ignoring serious harms.