Iran on Saturday night launched a barrage of dozens of ballistic missiles at Israel, with one missile impacting in the town of Tamra, east of Haifa, killing three people and injuring at least seven others, medics said.

The barrage was Iran’s first since the early morning hours. The salvo sent most of the country into shelters, with Home Front Command pushing phone alerts shortly after 11 p.m., but sirens were then only activated in the north and the Haifa area, as air defenses were activated to intercept the incoming attack.

One missile struck a two-story home in Tamra, killing three people and wounding seven.

One of the victims was reportedly a woman aged around 20.

Residents of the Arab Israeli city have long warned that there is a dearth of bomb shelters in the area, and that almost no homes have a safe room attached.

At around 11:45 p.m., Home Front Command gave the all-clear for people to leave shelters, though more barrages were expected overnight.

Iran had launched three major barrages of ballistic missiles at Israel Friday night and early Saturday morning. Some 80 people were reported hurt in the strikes, including three people who were critically injured and later succumbed to their wounds in the cities of Ramat Gan and Rishon Lezion. According to Magen David Adom, several more people were seriously hurt. The rest were lightly to moderately injured or suffered acute anxiety.

The three fatalities in Ramat Gan and Rishon Lezion were named Saturday as Etti Cohen Engel, Yisrael Aloni and Yevgenia Blinder.

Iranian media claimed hundreds of missiles were fired in the first barrage late Friday, while the Israel Defense Forces estimated that the actual number in all the attacks stood at some 200.

The three waves of attacks Friday overnight each consisted of dozens of missiles, according to the IDF, which declined to provide a specific number.

The IDF has called on the public not to publish the locations or footage of missile impacts. “The enemy monitors the footage to improve its attack capabilities,” the military said.

The enmity between Israel and Iran escalated into an unprecedented open conflict in the early hours of Friday morning as Israel launched a major offensive against Iran and its nuclear program, hitting nuclear sites, missile bases and top military officials.

Israel said it had no choice but to attack Iran, adding that it had gathered intelligence that Tehran was approaching “the point of no return” in its pursuit of a nuclear weapon.

The Israeli operation was expected to last several days at least, according to military officials, who added that the IDF was preparing for heavy fire from Iran, but asserted that “at the end of the operation, there will be no nuclear threat” from the Islamic Republic.