At least 51 people have been killed and around 100 injured after on-stage pyrotechnics caused a major fire in a nightclub in North Macedonia.

The blaze started at around 2.35am on Sunday morning during a music concert at the venue Pulse when a shower of sparks set fire to the roof, the interior ministry said in a press conference.

Video footage circulating online appears to show the moment when two flares went off close to the stage, with the sparks igniting the roof. In the video the band plays on unaware.

Another video showed people inside the venue trying to put out the flames with a fire extinguisher, with little effect.