Senate Republicans voted Wednesday to block a Senate Democratic proposal to fund the federal government through Oct. 31, to permanently extend enhanced health insurance premium subsidies that are due to expire in December, and to restore nearly $1 trillion in Medicaid funding cuts.

Republicans defeated a procedural motion to advance the legislation after voting against the bill itself Tuesday.

The measure failed by a vote of 47-53.

The Senate is also set to hold a procedural vote Wednesday on the GOP House-passed “clean” funding bill. That legislation also failed Tuesday.

The result of the vote was hardly in doubt as Senate Republicans have consistently criticized the bill as a “laundry list” of liberal priorities that would add $1.5 trillion to the deficit.

Senate Majority Leader John Thune (R-S.D.) said that “liberal, far-left activist groups” have hijacked the Democratic Party by insisting on using a short-term government funding measure to dramatically increase spending.

“They are demanding more than the Defense budget in their resolution to keep the government open for four weeks,” Thune said on the Senate floor.

Thune has said he’s willing to negotiate an extension of the enhanced subsidies under the Affordable Care Act (ACA) if Democrats agree to reopen the government, but he has emphasized that any extension of the subsidies needs to be paired with broader reform of the program to root out waste, fraud and abuse.

Senate Democratic Leader Chuck Schumer (N.Y.), meanwhile, said the House-passed funding bill is “partisan” because it wouldn’t do anything to address health care premiums, which are expected to rise significantly if the enhanced ACA subsidies are allowed to expire.

Schumer says health insurance premiums for people who buy their insurance through the ACA marketplace and receive enhanced financial assistance will rise by 114 percent on average.