Wall Street's main indexes opened muted on Wednesday in the absence of any strong cues to keep up the optimism around the prospects of early rate cuts that pushed the S&P 500 closer to its all-time high in the previous session.

The Dow Jones Industrial Average fell 26.71 points, or 0.07 percent, at the open to 37,518.62. The S&P 500 opened lower by 1.30 points, or 0.03 percent, at 4,773.45, while the Nasdaq Composite gained 15.09 points, or 0.10 percent, to 15,089.66 at the opening bell.