PORTLAND, Mich.—An interstate highway stretch in central Michigan has reopened following a massive pileup involving 150 vehicles in whiteout conditions that left 16 people hospitalized.

Interstate 96 in Ionia County reopened about 10 p.m. Saturday, about five hours after authorities reported the pileup in the eastbound lanes near Portland, a city more than 100 miles northwest of Detroit and roughly halfway between Lansing and Grand Rapids.

Michigan State Police officials said they closed both eastbound and westbound lanes just after 5 p.m. on Saturday following the pileup.

“Thankfully it appears that there are no serious injuries,” the MSP Sixth District in Grand Rapids wrote on Twitter. It posted on Twitter Sunday afternoon that 16 people were taken to a hospital.

A total of 150 vehicles were involved while 84 were damaged and 66 were not damaged after slideoffs, the later tweet said.

Officials posted photos of traffic backed up along the frigid roads after the crash.