Unpainted toenails. Chin hairs. Separating laundry by darks, lights and colors. Dress codes.

What do women in perimenopause and menopause have to say about these things? We do not care.

That is the message being spread by Melani Sanders, a 45-year-old mother of three and social media influencer in West Palm Beach, Fla., who has gained a huge following for celebrating women of a certain age who have stopped trying to please everyone. Hundreds of thousands of women around the world have responded to Ms. Sanders’ call to share what they no longer care about. They’re now all members of her “We Do Not Care” Club.

In viral videos, Ms. Sanders rattles off their responses. She peers out from behind her reading glasses (with another two pairs tucked into her T-shirt collar) and deadpans: “We do not care about arm fat. It’s not our fault our muscles grow down and not up.”

She looks down at her notebook, checking off that submission with a pen before moving onto the next one.

“We do not care if we don’t show up for the family cookout. Most of y’all have undiagnosed trauma that we honestly just don’t want to deal with right now.”