In June 1973, a C.I.A. employee wrote a memo at the request of William E. Colby, the agency’s director, listing various ways the C.I.A. had, to put it delicately, “exceeded” its charter over the years.

The seven pages matter-of-factly described break-ins at the French Consulate in Washington, planned paramilitary attacks on Chinese nuclear facilities and injections of a “contaminating agent” in Cuban sugar bound for the Soviet Union. The memo ended with an offhand aside about John A. McCone, the agency’s former director.

“Finally, and this will reflect my Middle Western Protestant upbringing, McCone’s dealings with the Vatican, including Pope John XXIII and Pope Paul VI, would and could raise eyebrows in certain quarters,” the author wrote.

It was just one paragraph in the roughly 64,000 pages the National Archives posted online this week as part of the latest — and supposedly final — release of its vast collection of documents related to the assassination of President John F. Kennedy.

But for some of the scholars who immediately started combing through the documents, the brief passage, seen unredacted for the first time, raised eyebrows for sure.

“This opens a door on a whole history of collaboration between the Vatican and the C.I.A., which, boy, would be explosive if we could get documents about,” said Peter Kornbluh, a senior analyst at the National Security Archive, an independent research center at George Washington University.