Ukraine’s foreign minister, Dmytro Kuleba, offered to resign on Wednesday amid plans by President Volodymyr Zelensky to restructure his cabinet in the biggest shake-up since Russia invaded more than two years ago.

At least six other senior leaders in Mr. Zelensky’s government have offered to resign, said Ruslan Stefanchuk, the speaker of Ukraine’s Parliament. More cabinet members were expected to offer their resignations on Wednesday, and a new list of ministers was to be presented on Thursday.

“Our state institutions must be set up in such a way that Ukraine will achieve all the results we need — for all of us,” Mr. Zelensky said in an address to the nation on Tuesday night. “To do this, we need to strengthen some areas in the government — and personnel decisions have been prepared.”

The restructuring appears to be the most far-reaching shake-up of Mr. Zelensky’s administration since Russia launched its full-scale invasion in February 2022, and it comes at a particularly precarious moment in the war, with Kyiv rushing reinforcements to its eastern front in an attempt to stabilize its defensive lines.

This is a developing story.