Sedona Prince graduated from high school outside Austin, Texas, as an all-American basketball player intent on making her mark. As she enters her final year in college, she has left an indelible imprint — but not on the court.

Prince, a 6-foot-7 center at Texas Christian University, became an avatar for the upheaval in college sports.

She is a plaintiff in two antitrust lawsuits, including House v. N.C.A.A., whose settlement agreement, if approved by a judge, would fundamentally change college sports by allowing schools to directly pay their athletes. Her video of a paltry weight room at the 2021 N.C.A.A. women’s basketball tournament laid bare the disparate treatment between men’s and women’s players, which has led to significant changes.

Prince, 24, has 2.6 million followers on TikTok, has testified before Congress and consulted with lawmakers who want to codify rights for college athletes. She is trying to organize college athletes to give them a more powerful voice, and fears that the settlement may be bad news for female and Olympic athletes.

Ramogi Huma, who leads the player advocacy group National College Players Association, also opposed the settlement on Thursday, saying it would allow schools to collude against revenue-sharing and restrict payments from collectives.

Complications from a broken leg just before college turned Prince from a self-conscious teenager into an activist. “I didn’t think I was every going to play basketball again because of my leg and so I was like, ‘you know what? I’m just going to try to make a change while I’m here,’” she said.