Richard Greenberg, who won frequent praise as the American Noël Coward for his sharp-witted plays about the manners and mores of urbane, sometimes smug New Yorkers, and who received a Tony Award in 2003 for “Take Me Out,” his play about a gay baseball player, died on Friday in Manhattan. He was 67.

His sister-in-law, Janet Kain Greenberg, said the cause of his death, in a hospice, was cancer.

A child of the middle-class Long Island suburbs, Mr. Greenberg rose to theater fame in the 1980s with a string of scripts that delved into the interior lives of the people he knew best: young, upwardly mobile urban professionals — yuppies, in the parlance of the time.

Works like “Eastern Standard” (1987) and “The American Plan” (1990), two of his first major plays, were incisive and biting, but never cruel. His goal was to examine the bourgeoisie, but never to épater them.

Having once aspired to be an architect himself, he used that profession as both an identity for many of his characters and an unspoken metaphor in his plays: How do the relationships we build on love and family and friendship bear up over time and under the stress of imperfect, if caustically funny, partners?

“We’re always trying to make a cogent story out of our existence,” Mr. Greenberg told Princeton Alumni Weekly in 2016, “and people in my plays often feel they have the story, but almost invariably they’re wrong.”