Federal prosecutors in Manhattan have charged two star luxury real estate brokers and their brother with participating in a long-running sex trafficking conspiracy, accusing them of repeatedly and violently drugging, sexually assaulting and raping dozens of women, according to an indictment made public on Wednesday.

The three were Oren Alexander, his older brother Tal Alexander, who until this summer were real estate agents in New York and Miami, and Alon Alexander, Oren’s twin who did not work in real estate.

The three were arrested at various residences in and near Miami Beach on Wednesday morning. The twins also face separate state felony charges of sexual battery connected to three separate assaults, according to arrest warrants obtained by The New York Times.

According to the federal indictment, Alon and Tal had conspired in the sex trafficking scheme since at least 2010. The brothers used their wealth and positions to create and take opportunities to rape and sexually assault women.

The brothers conspired with other men to arrange events and domestic and international trips to use as bait to recruit, entice and transport multiple women, whom they later raped, the indictment says.

The federal charges are expected to be announced later on Wednesday in Manhattan by Damian Williams, the U.S. attorney for the Southern District of New York, and James E. Dennehy, the head of the F.B.I.’s New York office.