Joy Reid’s evening news show on MSNBC is being canceled, part of a far-reaching programming overhaul orchestrated by Rebecca Kutler, the network’s new president, two people familiar with the changes said.

The final episode of Ms. Reid’s 7 p.m. show, “The ReidOut,” is planned for sometime this week, according to the people, who were not authorized to speak publicly. The show, which features in-depth interviews with politicians and other newsmakers, has been a fixture of MSNBC’s lineup for the past five years.

MSNBC is planning to replace Ms. Reid’s program with a show led by a trio of anchors: Symone Sanders Townsend, a political commentator and former Democratic strategist; Michael Steele, a former chairman of the Republican National Committee; and Alicia Menendez, the TV journalist, the people said. They currently co-host “The Weekend,” which airs Saturday and Sunday mornings.

An MSNBC spokesman, Richard Hudock, declined to comment. Ms. Reid did not respond to calls seeking comment.

The programming shake-up is the first major change made by Ms. Kutler, who was appointed president this month. Ms. Kutler has been drawing up a new programming lineup to jump-start the network’s ratings, which have outperformed rival CNN but lagged behind the longtime ratings leader, Fox News.