Miguel Uribe, the Colombian senator and presidential hopeful who was shot in the head at a campaign event two months ago in an attack that shocked the nation, has died at 39, according to a statement posted by his wife, María Claudia Tarazona.

Mr. Uribe had spent nine weeks in the hospital, undergoing multiple surgeries before succumbing to his injuries. The hospital had announced in a statement this weekend that Mr. Uribe’s condition had worsened and that he was experiencing bleeding in the brain.

The authorities have arrested four people in connection with the shooting, including a 14-year-old boy identified as the gunman, but have not disclosed a motive.

Prosecutors charged all four with attempted murder and illegal firearm possession. The three adults, Carlos Eduardo Mora, Katerine Martínez and William González face charges for using a minor to commit a crime.

All four have pleaded not guilty and have told prosecutors they were acting on orders from Elder José Arteaga, known as “El Costeño,” meaning “the man from the coast,” according to the attorney general’s office. Prosecutors have provided no further information about the man.

The killing of Mr. Uribe, a conservative politician and a grandson of a former president, is for many Colombians a traumatic reminder of the country’s troubled past — his mother, a famous journalist, was killed in 1991, when Mr. Uribe was a child, after being kidnapped by a drug cartel.

This is a developing story.

Ali Watkins contributed reporting.