Several members of Congress jumped into their cars and set off on hourslong road trips to make it to Washington by Wednesday ahead of an expected vote on President Trump’s domestic policy bill, after severe weather snarled air travel.

Thunderstorms and heavy rain had forced the cancellation of hundreds of flights to Washington-area airports, including Reagan National, according to the aviation tracker FlightAware. That left some members of the House, both yeas and nays on the bill, with no option but to drive.

Representative Nancy Mace, a Republican from South Carolina and a vocal supporter of Mr. Trump, piled into a van with her staff for an overnight drive to Washington.

“The reason I’m on the road is because my flights were canceled to D.C. and I didn’t want to take any chances,” Ms. Mace said, clad in pink pajamas, during a livestream on X from the van. As she held her dog, she asked viewers to send in recommendations for food stops on the way to Washington.

Ms. Mace also responded to questions about the bill, which aims to cut taxes as well as social safety net programs. She said she had been disappointed with some of the amendments made in the Senate, which narrowly passed its version on Tuesday.

Representative Russell Fry, another Republican from South Carolina, said he would not take any chances after flights were canceled because of the severe weather.