A jury in Massachusetts acquitted Karen Read of murder and manslaughter charges on Wednesday, ending a legal saga that has gripped the Boston area since the death of Ms. Read’s boyfriend, John O’Keefe, a Boston police officer, in January 2022.

Prosecutors had accused Ms. Read, 45, of intentionally hitting Mr. O’Keefe with her S.U.V. after an argument, and then leaving him to die in a blizzard.

Ms. Read tearfully embraced her attorneys after the verdict was announced in a courthouse in Dedham, Mass., as the cheers of hundreds of her supporters could be heard outside the courtroom.

The jury of seven women and five men, who began deliberating last Friday, convicted Ms. Read on one minor charge, operating a vehicle under the influence.

They delivered their verdict almost a year after an earlier trial in the case ended in a mistrial. That jury was unable to reach a consensus after five days of deliberation.

The case attracted a fervent following far beyond Boston, made up of true-crime fanatics and others who were fascinated by the elaborate theory advanced by Ms. Read’s lawyers. They argued that Officer O’Keefe, 46, had been killed at a late-night house party in Canton, Mass., that was hosted by another Boston police officer, and that corrupt investigators covered up the truth and framed Ms. Read for the murder.