Mayor Eric Adams’s former chief adviser on Thursday was charged for a second time with corruption in a sweeping set of indictments that accuse her of using her position to influence city agencies, collecting hefty payouts in the process.

The adviser, Ingrid Lewis-Martin, accepted more than $75,000 in bribes, according to prosecutors with the Manhattan district attorney’s office. They accused her of conspiring in schemes that included trading the approval of renovations of a residential property for thousands of dollars of catering for events at Gracie Mansion and City Hall, and helping to fast-track permit approvals for a Queens karaoke bar in exchange for $50,000 for her son.

“Lewis-Martin consistently overrode the expertise of public servants so she could line her own pockets,” the district attorney, Alvin Bragg, said in a news release. “While she allegedly received more than $75,000 in bribes and an appearance on a TV show, every other New Yorker lost out.”

The four new indictments, which in total charge seven people, most of whom are associates and supporters of Mr. Adams, come as he is just months from facing voters in his bid for a second term to be mayor of New York City.

Charged alongside Ms. Lewis-Martin were her son, Glenn D. Martin II; Jesse Hamilton, a former state senator whom Mr. Adams installed in a powerful city job; two influential supporters of the mayor, Gina and Tony Argento, siblings who run a prominent soundstage company; and two businessmen.

Both Ms. Lewis-Martin and her son were previously charged with bribery in an indictment handed up late last year.

When news of the charges broke on Wednesday, a spokeswoman for the mayor, Kayla Mamelak Altus, said Mr. Adams “was not involved in this matter and has not been accused of or implicated in any wrongdoing.”

“Ingrid Lewis-Martin no longer works for this administration,” she added.

This is a developing story and will be updated.