Gov. Ron DeSantis had just taken office in 2019 when the University of Florida lured Neil H. Buchanan, a prominent economist and tax law scholar, from George Washington University.

Now, just four years after he started at the university, Dr. Buchanan has given up his tenured job and headed north to teach in Toronto. In a recent column on a legal commentary website, he accused Florida of “open hostility to professors and to higher education more generally.”

He is not the only liberal-leaning professor to leave one of Florida’s highly regarded public universities. Many are giving up coveted tenured positions and blaming their departures on Governor DeSantis and his effort to reshape the higher education system to fit his conservative principles.

The Times interviewed a dozen academics — in fields ranging from law to psychology to agronomy — who have left Florida public universities or given their notice, many headed to blue states. While emphasizing that hundreds of top academics remain in Florida, a state known for its solid and affordable public university system, they raised concerns that the governor’s policies have become increasingly untenable for scholars and students.

The University of Florida said that its turnover rate is not unusual and remains well below the 10.57 percent national average. Hiring, it said, has also outpaced departures. Florida State University and the University of South Florida released similar figures.

Governor DeSantis’s office did not respond to requests for comment. But Sarah D. Lynne, chair-elect of the University of Florida’s faculty senate, said that little has changed except that her campus has become the focus of national politics. Most people who leave, she said, do so for reasons that have nothing to do with politics.