The maximum-security prison known as Angola, notorious for a history of violence and harsh conditions, has long been the repository for Louisiana’s worst offenders. Most inmates arrive with life sentences.

Now, the prison, officially the Louisiana State Penitentiary, will also hold immigrants who have been detained as part of the Trump administration’s widening crackdown, federal and state officials said on Wednesday.

Like the prison itself, Gov. Jeff Landry of Louisiana said, the immigrant detention center there will house “the worst of the worst,” allowing federal immigration authorities to “consolidate the most violent offenders into a single deportation and holding facility.”

“If you don’t think that they belong in somewhere like this,” Mr. Landry, a Republican, said in a news conference on Wednesday, “you’ve got a problem.”

Officials said that as of Wednesday, 51 male detainees had been moved into the facility, and that by later this month, it would hold more than 200. It has a total capacity of about 400. The immigrants detained at Angola will be “completely isolated” from the rest of the prison’s population, and the center will be run by ICE contractors, the governor said.

Kristi Noem, the homeland security secretary, said at the news conference that immigrants detained at Angola would be “high risk” individuals, naming several examples that included men convicted of offenses including murder, sexual assault, battery and possessing large troves of child sexual abuse imagery.