By his own rough count, the filmmaker Barry Jenkins has seen the 1994 animated movie “The Lion King” around 155 times, many of those viewings with two young nephews and a well-worn VHS tape.

So when he was asked to direct the latest installment of the franchise, “Mufasa: The Lion King,” he was already pretty familiar with the story.

Who isn’t? “When anybody takes their baby and holds it up like this” — he paused to raise his arms overhead, cupping his hands as though presenting a small but celebrated cub — “you know it’s ‘The Lion King,’” he said. “There are very few things that have that level of cultural penetration.”

Familiarity aside, very few things in Jenkins’s career would seem to point to a big Disney animated feature. The director, 44, broke out in 2016 with “Moonlight,” a small-budget coming-of-age film set in Miami at the height of the crack epidemic. It went on to win three Oscars, including one for best picture that, notoriously, was announced only when a “La La Land” producer realized onstage that the wrong movie (his) had been called. Jenkins followed that up in 2018 with “If Beale Street Could Talk,” a romantic drama based on the 1974 James Baldwin novel about childhood sweethearts confronting a nightmare when the young man is unjustly accused of rape.

And then Jenkins directed the 10-episode 2021 mini-series “The Underground Railroad,” an adaptation of Colson Whitehead’s Pulitzer Prize-winning novel, which imagines the abolitionist-era network of escape routes as a literal railway system. “In terms of emotional scope and just the practical logistics of filmmaking, that was by far the most massive thing I’d done,” he said.

“Mufasa,” at least in terms of its fandom and the accompanying scrutiny, is likely to be even bigger. Disney is planning a December release for the film, which tells the story of how Mufasa grew up and came to power before siring Simba. It will serve as a prequel to three previous “Lion King” iterations: the original movie from 1994, the 2019 remake and the long-running Tony Award-winning musical. “I don’t know if pressure is the right word,” Jenkins said, “but you do go, OK, I have to live up to this standard that was set by these people who made these films before me.”