More Americans are surviving cancer, but the disease is striking young and middle-aged adults and women more frequently, the American Cancer Society reported on Thursday.

And despite overall improvements in survival, Black and Native Americans are dying of some cancers at rates two to three times higher than those among white Americans.

These trends represent a marked change for an illness that has long been considered a disease of aging, and which used to affect far more men than women.

The shifts reflect declines in smoking-related cancers and prostate cancer among older men and a disconcerting rise in cancer in people born since the 1950s.

Cancer is the second leading cause of death in the United States, but the leading cause among Americans under 85. The new report projects that some 2,041,910 new cases will occur this year and that 618,120 Americans will die of the disease.

Six of the 10 most common cancers are on the rise, including cancers of the breast and the uterus. Also on the rise are colorectal cancers among people under 65, as well as prostate cancer, melanoma and pancreatic cancer.