Sheena Wright, a longtime ally of Mayor Eric Adams, has resigned from her post as first deputy mayor, according to people with knowledge of the matter, making her the seventh senior official to leave the administration during a time of crisis in New York City government.

Ms. Wright is expected to be replaced by Maria Torres-Springer, the mayor’s current deputy mayor for housing, economic development and work force, according to those people. One of the people said Ms. Wright planned to serve until the end of the month. Mr. Adams is expected to make the announcement before his regular Tuesday media availability.

“We are grateful for First Deputy Mayor Wright’s years of service to the city and all she has done to deliver for children, families, and working-class New Yorkers,” Mr. Adams said in a statement that was expected to be circulated on Tuesday. “She is an exceptional leader who assembled a strong team and constantly demonstrated a bold vision for this city.”

News of Ms. Wright’s departure comes two weeks after federal prosecutors unsealed a five-count corruption indictment against the mayor.

It also follows the resignation announcements of her brother-in-law, Philip B. Banks III, the deputy mayor for public safety, and her husband, David C. Banks, the schools chancellor.