Two high-ranking New York Fire Department chiefs were arrested early Monday on federal bribery and corruption charges that accuse them of taking nearly $100,000 apiece in a scheme to expedite safety inspections, people with knowledge of the matter said.

The two chiefs, whose homes and offices at Fire Department headquarters were searched by federal agents and city investigators in February, are expected to appear in United States District Court in Manhattan later on Monday, the people said.

The chiefs — Brian E. Cordasco, 49, and Anthony M. Saccavino, 59 — were responsible for overseeing safety inspections on building projects. Neither man could immediately be reached for comment Monday morning. It was unclear whether either had retained lawyers in the matter, which has been under investigation since last summer.

There is no indication that the case is related to any of the four separate federal corruption investigations swirling around Mayor Eric Adams, his campaign and some of his most senior aides. The inquiry focused on the mayor is being conducted by the same agencies that investigated the chiefs, however, and also relates in part to fire safety inspections, several of the people said.

The charges against the chiefs are likely to increase the pressure on Mr. Adams and his administration as it faces a welter of corruption investigations that led last week to the resignations of two top officials in three days.