A woman was killed and four children seriously hurt when a fire ripped through a Brooklyn home early Tuesday, officials said. 

The blaze erupted inside the three-story house on Fountain Avenue near Liberty Avenue in Cypress Hills around 2:15 a.m., authorities said. 

The woman, whose age was not immediately known, was discovered inside the home and pronounced dead on the scene. 

Three girls – ages 10, 14 and 17, as well as a 9-year-old boy – were rushed to Brookdale University Hospital Medical Center, each in either serious or critical condition, cops said. 

A man, whose age is also unknown, was taken to Nassau University Medical Center, where he was listed in stable condition. 

All six victims are believed to be related, though that has not yet been officially confirmed, cops said. 

A dozen FDNY units – including 60 firefighters and EMS workers – responded to the scene. 

The blaze was placed under control within about an hour, fire officials said. 

The cause remained under investigation later in the morning.