Dead & Company has taken over Sphere.

The Grateful Dead offshoot launched their Dead Forever residency at the immersive venue in Las Vegas on May 16, treating the band’s devoted Deadheads to a trippy, once-in-a-lifetime experience.

During their three-night opening weekend, Bob Weir, Mickey Hart, Bill Kreutzmann, John Mayer, Oteil Burbridge and Jeff Chimenti ran through classic songs including “Fire on the Mountain,” “Truckin'” and “Franklin’s Tower” while performing in front of a 160,000-square-foot wraparound screen featuring their signature mind-bending visuals.

Celebrities in the audience included Mayer’s best friend Andy Cohen as well as Diplo, Miles Teller, Chantel Jefferies and Cruz Beckham.

Variety wrote in its review of the first night that the “most integral” piece of the four-hour show was the Dead’s iconic skeleton “rising from the grave, doing a little jig and grinningly mounting a motorcycle to go journeying through a psychedelic landscape.”

The Post exclusively reported in December 2023 that Dead & Company had been in talks to do a residency at Sphere following U2’s 40-date run, which began in September.

Dead & Company, which formed in 2015, confirmed the news in January, revealing that they will call the state-of-the-art arena home through July 13.

See the most kaleidoscopic photos from the opening weekend of Dead Forever below.