The Owls struggled to reach the Sweet 16 despite the gift of playing Fairleigh Dickinson instead of Purdue.

And now, the kids from Conference USA play a power conference team for the first time in four months.

Gametime: 9 p.m. Eastern

TV: TBS

Live Stream: March Madness Live app, fuboTV, Sling, YouTube TV, Hulu + Live TV

After physically dominating Duke in Round 2 — limiting the Blue Devils to 52 points — the Vols will have even more success overpowering the smaller mid-major.

The team with the best 3-point defense in the nation will disrupt an offense that lives behind the perimeter, and earn multiple second-chance points on the offensive glass, minimizing Rick Barnes’ opportunities for self-inflicted damage.

The pick: Tennessee (-5.5) over Florida Atlantic