Shohei Ohtani’s first Dodgers home run came against Los Angeles’ biggest rivals.

The two-time MVP smacked his first long ball with his new club in the seventh inning on Wednesday night against the Giants, adding to the Dodgers’ lead in a tightly contested ballgame that they won, 5-4.

Ohtani hadn’t gotten off to the strongest of starts through the team’s first eight games, going 8-for-33 with a .631 OPS and just three extra-base hits.

But with one hit already on the books, Ohtani was ready for more as he faced left-handed reliever Taylor Rogers and the Dodgers up 4-3 in the seventh.

The two-way Japanese superstar slugged a 3-1 offering on the outside corner over the right-center field wall to put the Dodgers up by two runs.

As the ball went 430 feet at 105.6 mph, SportsNet LA play-by-play voice Joe Davis brought some extra excitement for his call.

“Drilled, oh oh, Shohei Ohtani — first Dodgers home run!” Davis said in amazement at the blast.

After a brief interjection from Orel Hershiser, the two let the game breathe as the exuberant 52,746 fans at Dodger Stadium reveled in the moment.

The fan who ended up with the ball was particularly excited as a woman in a Dodgers bucket cap had the ball in her right hand and held it up triumphantly as the fans near her celebrated.

After Ohtani took his trot around the bases, he headed toward the dugout and was greeted by teammate Teoscar Hernandez — who threw a big handful of sunflower seeds right in his face.

The home run proved to be the difference, as the Dodgers won their second straight one-run contest and third overall against the Giants.