Missouri police are probing a slew of fresh tips about the disappearance of emergency-room Dr. John Forsyth, who mysteriously vanished last week, his brother told The Post on Tuesday.

Richard Forsyth said his family received three possible leads from the public and passed the information on to cops, hoping it will help shine a light on what happened to the beloved 49-year-old doctor and father of seven after he worked a night shift at Mercy Hospital in Cassville.

One of the most “credible” tips came from a woman who says she spotted someone matching Forsyth’s description at Casville’s South Park, near the area where police found his missing vehicle, the sibling said.

John’s car was found about 12:15 p.m. March 21 at the Cassville Aquatic Center.

Richard said his brother’s phone was discovered in the car along with his keys, wallet and cash.

The sibling noted that Forsyth was wearing a black button-down shirt with white long sleeves and gray jeans when he went missing and that the tipster claimed she saw someone wearing that exact outfit at the hiking trail south of the aquatic center at around 12:30 p.m.

The woman said the man she saw appeared to be walking in a hurry, Richard said.

The area had been extensively searched, with no signs of the doctor turning up, after his car was found at the parking lot, which is less than a mile from the hospital.

Richard said another hot tip came in about a possible sighting at the Roaring River Hatchery, a popular tourist spot in the Roaring River State Park, located about 8 miles south of the aquatic center.

A tipster claimed to have seen the doctor at the nature trail around 11:15 a.m., about an hour before his car was seen parking at the aquatic center. Richard said investigators are looking to see if the hatchery has any footage of Forsyth from that morning.

The final tip revolved around the aquatic center’s parking lot, where a woman claimed to have seen a blue van with tinted windows driving back and forth around the area where police found Forsyth’s car.

Richard said that while it could ultimately be unrelated to his brother’s case, it did raise suspicions, given Forsyth’s car was located in a remote area of the parking lot.

The sighting of the van comes after security footage from the aquatic center showed Forsyth’s Infiniti sedan arriving at the parking lot before a white SUV pulled up near him.

Richard said it was not immediately clear if the white SUV played a role in his brother’s disappearance, noting that the footage from the parking lot appeared to be unreliable and wouldn’t be able to tell if Forsyth traveled back-and-forth from the lot.

“We’re all worried but incredibly grateful for all the support and tips coming in about John,” Richard said. “The support has been overwhelming.”

He described his brother as a loving and generous man who adored mathematics and would have white boards all over his house filled with coding lines and ideas.

The two brothers had founded their own cryptocurrency company in 2019, OnFo, to help those in developing countries break into the then-booming market after Forsyth made his own wealth on Bitcoin. Richard lamented that without his brother, the company will likely crash.

Despite the search for Forsyth entering its second week, Richard said he remains hopeful that his brother will turn up safe and sound and return to his fiancee and seven children.

“It’s been hard on our family, but everyone is hoping for the best outcome,” Richard said.

The Missouri State Highway Patrol, which is leading the case, did not immediately respond to the Post’s request for comment Tuesday.