Madonna’s brother, Christopher Ciccone, has died. He was 63.

Christopher passed away of cancer on Friday in Michigan, his rep confirmed to TMZ.

The Post has reached out to Madonna and Christopher’s reps for comment.

Christopher’s death comes less than two weeks after the passing of his and Madonna’s stepmother, Joan Clare Ciccone. Joan also died of cancer.

“Joan Clare Ciccone passed away peacefully early in the morning of September 24th, 2024, after a brief encounter with a very aggressive cancer,” an online obituary stated. “She will be terribly missed by her family and friends whose lives she enriched with her enthusiasm, joy and love.”

Joan was married to Christopher and Madonna’s father, Silvio, for 58 years. 

Their mother, also named Madonna, died in December 1963 at the age of 30.

More to come…