THE AMERICA ONE NEWS
Sep 21, 2025  |  
0
 | Remer,MN
Sponsor:  QWIKET 
Sponsor:  QWIKET 
Sponsor:  QWIKET: Elevate your fantasy game! Interactive Sports Knowledge.
Sponsor:  QWIKET: Elevate your fantasy game! Interactive Sports Knowledge and Reasoning Support for Fantasy Sports and Betting Enthusiasts.
back  
topic


NextImg:James Conner carted off field in potential Cardinals injury nightmare

James Conner suffered a scary-looking injury during the third quarter of the Cardinals’ game against the 49ers. 

The running back was hit low on a rushing attempt when his ankle got trapped under him and appeared to bend in an awkward position as he was brought down by a 49ers player, immediately causing an obvious amount of pain for Conner. 

Arizona Cardinals running back James Conner right, is injured while being tackled by San Francisco 49ers defensive tackle Jordan Elliott, top, and cornerback Chase Lucas. AP

Conner grabbed for his lower right leg and after the Cardinals’ medical staff came out to check on him, he was carted off the field as his teammates came onto the field to show their support and concern for their injured teammate.

Arizona quickly ruled Conner out for the remainder of the game with an ankle injury. 

James Conner is taken off the field on a cart during the third quarter against the San Francisco 49ers at Levi’s Stadium on September 21, 2025 in Santa Clara, California. Getty Images

Conner left the game with nine carries for 22 yards and an additional 15 yards on three receptions. 

The running back had rushed for 73 yards and a touchdown through the first two games and had five catches for 23 yards and a touchdown during that same span. 

make every NFL game pay off
underdog fantasy logo
Underdog Fantasy

Underdog is where football fans become winners.

Use promo code NYPOST5 to get $50 in site credits when you play $5!

Must be 18+ (19+ in AL, NE; 19+ in CO for some games, 21+ in AZ and MAZ) and present in a state where Underdog operates. Concerned with your play? Call 1-800-GABMLER or visit http://www.ncpgambling.org. NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or text HOPENY (467369). New York Post receives revenue from affiliate and advertising partnerships for sharing this content and when you make a purchase. The Underdog promo code might vary by location.

Conner is an important piece of the Cardinals’ offense and he leaves them somewhat thin at the position, with Trey Benson and Emari Demercado next on the depth chart. 

James Conner runs the ball against the Carolina Panthers during the third quarter. Getty Images

Benson is expected to slot into the starter role, depending on how long Conner could potentially be out for. 

The second year back did have 69 total yards in Week 1 and 14 in Week 2.