Hundreds of anti-Israeli protesters wreaked havoc in Lower Manhattan on Monday, storming the Brooklyn Bridge and grinding traffic to a halt on its Manhattan-bound side as cops in riot gear fought to contain the unrest.

The marchers converged on the historic span around 3:45 p.m., immediately disrupting cars and prompting NYPD cops to swarm the area and begin cuffing at least 20 of them.

Photos posted on social media shows the massive mob invading the span during the disruptive rally — only the latest in the Big Apple since the Oct. 7 Hamas terror attack on Israel and the subsequent counter-offensive by the Jewish state in the Gaza Strip.

“A bunch of people already got over,” a protester on the bridge told The Post. “They started arresting people here.”

The NYPD said Monday afternoon that one person had been arrested, although no charges had yet been filed.

Meanwhile, police in riot gear blocked the bridge to keep the protesters away from City Hall.

Rowdy pro-Palestinian demonstrations have rocked the city in recent months, with protesters disrupting Midtown holiday festivities and converging on Big Apple landmarks.