Five burglars stole $2.5 million in luxury watches – plus a safe holding $160,000 – during a Memorial Day heist at a Staten Island store, police said. 

Surveillance footage, released by cops late Wednesday, shows one of the crooks using what appears to be a crowbar to pry open the door of The Wrist Watcher on Arthur Kill Road near South Bridge Street in Charleston. 

The other four followed him inside, one walking with a dolly to haul loot during the 10:30 p.m. burglary. 

The crew snatched the hefty stash of watches and the safe before taking off, police said. 

No one was hurt.

The NYPD was unable to say Thursday how many watches were stolen or their brands. 

But the company’s website notes that high-end watches from luxe brands including Rolex, Audemars Piguet, Richard Mille and Patek Philippe are sold there. 

Cops released the footage and surveillance images to ask for the public’s help in identifying the suspects.