Police shot a knife-wielding man after he allegedly stabbed a uniformed security guard in Queens Thursday, cops said.

The violence broke out just before 3:45 p.m. near 89-62 164 St. in Jamaica, where the unknown man stabbed the guard in the chest, police said.

He allegedly threatened the officers with the knife when they responded, and the cops shot the man, police said.

Both the attacker and guard were taken to the hospital, where they are in stable condition.

It was unclear what sparked the violence.

The police shooting comes hours after police shot an armed homeowner, who they say “charged” at officers, as they were responding to a burglary call at his home, according to police officials.