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Sep 12, 2025  |  
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NextImg:bet365 bonus code NYPBET: Bet $5, get $300 in bonus bets win or lose for Colorado vs. Houston

Deion Sanders and the Colorado Buffaloes take on the undefeated Houston Cougars in their Big 12 opener on Friday night.

Colorado rebounded from a loss to Georgia Tech in Week 1 with an unfussy win over Delaware in Week 2.

Houston comes into Friday night at 2-0, and looks to take a big step forward in Willie Fritz’s second year in charge.

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Houston has raised expectations thanks to a 2-0 start, but the Cougars have yet to face a tough opponent.

Runaway wins against Stephen F. Austin and Rice are nice, but they’ll be stepping up in weight class against Colorado, who are looking to prove they don’t need Shedeur Sanders and Travis Hunter to compete in the wide-open Big 12.

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Michael Leboff is a long-suffering Islanders fan, but a long-profiting sports bettor with 10 years of experience in the gambling industry. He loves using game theory to help punters win bracket pools, find long shots, and learn how to beat the market in mainstream and niche sports.