Mama mia!

Emmy Award-winning actress Amanda Seyfried — who recently starred as Elizabeth Holmes in “The Dropout” on Hulu and is now in Apple TV+’s “The Crowded Room” with Tom Holland and Emmy Rossum — has just granted Architectural Digest a tour of her newly renovated top-floor pied-à-terre at the famed Apthorp on the Upper West Side.

It’s an upgrade from her Devonshire House condo, which she sold last year for $3.4 million.

Seyfried shares the home with hubby Thomas Sadoski — they met while starring in an off-Broadway play — and their two kids. They also own a home in LA and a farm in the Catskills.

The crowning UWS abode is a combination of three former staff units designed by Sarah Zames and Colin Stief, founders of Brooklyn-based interior design studio General Assembly. 

Built in 1907 for William Waldorf Astor, and modeled after the Palazzo Pitti in Florence, the landmarked Apthorp is on the National Register of Historic Places. 

The building, with its gilded gates and grand courtyard, takes up an entire city block between 78th and 79th streets.

It has been home to many celebrities over the years, including the late New York Post scribe turned author and filmmaker Nora Ephron, Rosie O’Donnell, Cyndi Lauper, Conan O’Brien, George Balanchine, Al Pacino, Lena Horne and Douglas Fairbanks, Sr.

Its past is as colorful as the city itself. The Apthorp, which was a rent-stabilized and rent-controlled building before its condo conversion in the aughts, was once the subject of a state attorney general’s probe.

Its owners have included an Uzbekistan-born diamond king, Lev Leviev, who is close to Russian dictator Vladimir Putin.

Seyfried purchased the units for $2.52 million in 2019 under Jenni Birtchnell, LLC, which was also tied to her Devonshire House apartment.

It overlooks Alchemy Properties’ 378 West End Ave., where a penthouse that was last asking $25 million just went into contract.