JK Rowling praised Wes Streeting for confirming the Labour Government was committed to retaining the ban on puberty blockers for children.
The Harry Potter author described her "relief" at the decision, saying the Health Secretary had taken a "humane, considered" approach to the issue.
On Sunday the Labour minister had said on social media: "Children’s healthcare must always be led by evidence.
Medicine given to children must always be proven safe and effective first. I know there’s lots of fear and anxiety."
He added:"We don’t yet know the risks of stopping pubertal hormones at this critical life stage. That is the basis upon which I am making decisions.
"I am treading cautiously in this area because the safety of children must come first."
Streeting concluded: I know there’s lots of fear and anxiety. I am determined to improve the quality of, and access to, care for trans people."
Amid backlash to the statement from trans activists, Rowling gave her support to the Ilford North MP's decision.
She said: "It is a mark of how febrile and often vicious the discourse around child transition has become that this humane, considered [response] from Wes Streeting comes as such a relief."
Experts are urging the Labour Party to "abolish" the two-child benefit cap on benefit payments from the Department for Work and Pensions (DWP) as soon as possible.
Research conducted by The Resolution Foundation found that the policy is set to push the majority of large families into poverty within the next five years.
Based on new DWP data, the think tank discovered 38 per cent of household with three children were affected by the imposed cap in April 2024.
JK Rowling's praise for Wes Streeting comes after repeated clashes between the best-selling author and the Labour Party on trans rights.
Less than two weeks before the General Election, Rowling criticised the party for "abandoning" women with its stance on the rights of transgender people.
"As long as Labour remains dismissive and often offensive towards women fighting to retain the rights their foremothers thought were won for all time, I'll struggle to support them," she wrote in the Times.
"For left-leaning women like us this isn't, and never has been, about trans people enjoying the rights of every other citizen and being free to present and identify however they wish.
"This is about the right of women and girls to assert their boundaries. It's about freedom of speech and observable truth."