An American man who went on a solo-hike has gone missing from a Greek island just days after Michael Mosley vanished in similar circumstances.

Eric Calibet, 59, a retired police officer, embarked on a challenging four-hour hike on the island of Amorgos, from Aegiali to Katapola, at around 7am local time according to residents.

When he had not returned eight hours later, a friend reported him missing to the police. Authorities have not been able to contact Calibet via either of his two cell phones.

His disappearance comes just days after television doctor Mosley died on the neighbouring island of Symi after going on a similar solo-hike - his death has been down to natural causes and he died the same day he was reported missing.

An American man who went on a solo-hike has gone missing from a Greek island just days after Michael Mosley vanished in similar circumstancesMunicipality of Amorgos/Getty

Mosley’s body was found near the entrance to a cave just metres away from Agia Marina beach after an extensive four-day search.

The two disappearances come amid a record early heatwave for Greece, which has seen the temperature rise as high as 43C in Athens.

Amorgos, the island where Calibet was holidaying, is subject to a “severe high-temperature warning” this week.

Authorities on the island have released a photo of the missing American as part of the search and rescue operation.