Chicago's mayoral candidates will vie for the seat on Tuesday, February 28, 2023. (Fox & Friends First/Screengrab)
Recent polls showed her trailing two of her main Democratic rivals: former Chicago Public Schools CEO and city budget director Paul Vallas by 19 points, and Brandon Johnson, a member of the Cook County Board of Commissioners, by two points. She is in a dead heat with Democratic Rep. Jesus "Chuy" Garcia who represents Illinois's 4th Congressional District.
Garcia previously ran for mayor in 2015, forcing a run-off election before ultimately losing to now-former Chicago Mayor Rahm Emanuel.
Chicago mayor Lori Lightfoot, left, and her spouse Amy Eshleman wave to supporters during Women for Lori Rally in Chicago, Saturday, Feb. 25, 2023. (AP Photo/Nam Y. Huh)
Vallas has portrayed himself as the law and order candidate amid concern over the rising crime plaguing the city, and has received support Chicago's police unions. He has also been a sharp critic of Lightfoot's handling of crime.
It's possible the results won't be known for several days because Chicago law allows for mail-in ballots received after election day to be counted as long as they are postmarked by Feb. 28 and received by Mar. 14.
A Chicago Police Department vehicle is shown patrolling the streets of the Windy City. (Beata Zawrzel/NurPhoto via Getty Images)
Should none of the nine candidates receive an outright 50% of the vote, the race will head to a runoff election on Apr. 4.
Fox News' Timothy H.J. Nerozzi contributed to this report.