Multiple individuals in the vehicle were shot.
Police said the vehicle stopped near the 111 Street exit ramp, and two people were found dead inside. Four others were rushed to a hospital, where one of the victims later died.
CHICAGO FIERY DRAG RACING CRASH LEAVES 3 DEAD, INCLUDING 2 TEENAGERS
An adult male and two children, a boy and a 1-year-old girl, died in the shooting, the station reported. The girl was identified as Amara Hall.
An adult male and two children, including a 1-year-old baby, were killed in the shooting. Three others were injured. (FOX32 Chicago WFLD)
The adult male was 19 years old, and the boy was 14, WLS-TV reported. The other victims included an adult woman and two boys, ages 13 and 14, who were all reportedly hospitalized in serious but stable condition.
The shooting happened Sunday around 10:30 p.m. on I-57 in Chicago. (FOX32 Chicago WFLD)
The expressway was closed for nearly six hours following the shooting.
No arrests have been made as of Monday afternoon.