The men, who live in Michigan, were identified as Armani Kelly, Montoya Givens and Dante Wicker.
They were scheduled to perform at a party at Lounge 31 in Detroit on Jan. 21, but the appearance was canceled.
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Kelly's fiancée said phone calls, text messages and social media contacts have not been answered since that night.
Three Detroit rappers have been missing for ten days after canceling a gig last minute due to an equipment issue.
"I just beg for help, for anything. I need answers and, if it comes to it, I need closure, because I will never forget and I will never stop," Taylor Perrin said.
She said Kelly was working, taking college classes and polishing his rap skills — a turnaround after a robbery case.
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"Armani did his time and came out as a whole new person," Perrin told The Detroit News.
McGinnis said police are checking license plate readers and security video to try to solve the mystery.
"I’m confident that using those tools will help us get the answers that these families deserve," he said.