Today is Saturday, Sept. 28, the 272nd day of 2024. There are 94 days left in the year.

On Sept. 28, 1928, Scottish medical researcher Alexander Fleming discovered penicillin, the first effective antibiotic.

In 1781, American forces in the Revolutionary War, backed by a French fleet, began their successful siege of Yorktown, Virginia.

In 1941, Ted Williams became the most recent American League baseball player to hit over .400 for a season, batting .406 for the Boston Red Sox.

In 1962, a federal appeals court found Mississippi Gov. Ross Barnett in civil contempt for blocking the admission of James Meredith, a Black student, to the University of Mississippi.

In 1995, Israeli Prime Minister Yitzhak Rabin and PLO chairman Yasser Arafat signed an accord at the White House ending Israel’s military occupation of West Bank cities and laying the foundation for a Palestinian state.

In 2000, capping a 12-year battle, the U.S. government approved use of the abortion pill RU-486.

In 2020, the worldwide death toll from the coronavirus pandemic reached 1 million, according to a count by Johns Hopkins University.

In 2022, Hurricane Ian barreled ashore in southwestern Florida as a massive Category 4 storm. About 2.5 million people were ordered to evacuate before the storm hit the coast with maximum sustained winds of 150 mph (241 kph).