The Orioles’ first game against the Toronto Blue Jays in 2023 was similar to many the teams have played over the past few years.

Not as much in the fact that Baltimore won the game, as the Orioles haven’t posted a winning record against their American League East foe since 2017. Rather, it was Ryan Mountcastle blasting a home run off Blue Jays pitcher Yusei Kikuchi that evoked familiar feelings.

Mountcastle clobbered a three-run home run off Kikuchi in the third inning to propel the Orioles to a 6-2 win over the Blue Jays at Rogers Centre. There are few pitchers, teams or venues the Orioles slugger is more effective against than those three.

The 26-year-old entered Friday’s series opener with a 1.014 OPS against Toronto in his four-year career — his best mark off any team he’s tallied at least 50 plate appearances against. But it’s his success versus Kikuchi that is even more profound, as Mountcastle is now 5-for-10 with a double, four home runs — yes, four — and eight RBIs against the Japan native.

Mountcastle’s long ball was all pitcher Kyle Gibson needed, as the veteran right-hander delivered one of his best starts as an Oriole. Gibson pitched seven innings of one-run ball to end his three-game losing streak.

Anthony Santander hit a solo shot in the sixth, Adam Frazier added two insurance runs in the ninth with a blast of his own and relievers Yennier Cano and Félix Bautista shut the door behind Gibson.

Cano’s scoreless innings streak came to an end at 21 2/3 innings after he allowed a run in the eighth, but he stranded a runner at third after getting into trouble to hold the lead at 4-2. Frazier’s blast gave the Orioles extra cushion, but manager Brandon Hyde still turned to Bautista to close the game in a nonsave situation.

Baltimore (29-16) is now 7-6 against AL East teams after opening the season 2-4. From 2019 to 2022, the Orioles went 24-43 versus Toronto. They are 1-0 against the Blue Jays this year.

This story will be updated.

Orioles at Blue Jays

Saturday, 3:07 p.m.

TV: MASN

Radio: 97.9 FM, 101.5 FM, 1090 AM

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