President Donald Trump's tax cut and spending bill came down to the wire as Senate Republican leaders scrambled to get all GOP members on board before the final vote Tuesday.

In the end, three long-serving GOP members, Susan Collins of Maine, Rand Paul of Kentucky and Thom Tillis of North Carolina voted against, forcing Vice President JD Vance to break a 50-50 tie.

Each of the three has explained their reasons for bucking the president.

One of the mostly closely watched as the vote neared was Collins, who had been on the fence due to the bill's proposed Medicaid cuts.

"Approximately 400,000 Mainers – nearly a third of the state's population – depend on this program," she said in a statement after voting no. "A dramatic reduction in future Medicaid funding, an estimated $5.9 billion in Maine over the next 10 years, could threaten not only Mainers' access to health care, but also the very existence of several of our state's rural hospitals."

Collins added that the bill had "additional problems."

"The tax credits that energy entrepreneurs have relied on should have been gradually phased out so as not to waste the work that has already been put into these innovative new projects and prevent them from being completed," she said.

Tillis has been extremely vocal in his opposition sine the weekend, drawing attention for a passionate floor speech citing Medicaid provisions he claimed would hurt his North Carolina constituents.

During a closed-door GOP conference meeting two weeks ago, Tillis is reported to have made the point that Medicaid coverage for more than 600,000 North Carolinians would be at risk under the Senate's proposal and asked his colleagues to consider how the policy would affect their own states -- even providing state-specific data on a handout.

"I just encouraged other members to go to their states and just measure how ... take a look at the proposed cuts and tell me whether or not you can absorb it in the normal course of business, and in many cases, you're gonna find that you can't," Tillis told reporters at the Capitol last week.

Trump lashed out against Tillis on his social media platform and to the press and threatened to field primary challengers. Tillis announced on Saturday that he would not seek reelection.

Paul, a staunch advocate for keeping spending and the debt ceiling in check, posted on X that he wanted the bill to include a 90% reduction in the ceiling.

"No earmarks. No handouts. Just real fiscal reform. I wasn't looking for favors. I wasn't horse-trading. I was fighting for the American people and against our out-of-control debt," he said.

"Bottom line: I offered my vote for fiscal sanity. Congress chose to sell out taxpayers instead. Only once the bill is released, we will know what the true price was," Paul added.